翻訳と辞書 Words near each other ・ Complete measure ・ Complete metric space ・ Complete mixing ・ Complete Music Update ・ Complete numbering ・ Complete Onside Soccer ・ Complete partial order ・ Complete Poems ・ Complete protein ・ Complete Psionic ・ Complete quadrangle ・ Complement component 1s ・ Complement component 2 ・ Complement component 3 ・ Complement component 4 ・ Complement component 4B ・ Complement component 5 ・ Complement component 5a ・ Complement component 6 ・ Complement component 7 ・ Complement component 9 ・ Complement control protein ・ Complement deficiency ・ Complement factor B ・ Complement factor I ・ Complement fixation test ・ Complement graph ・ Complement membrane attack complex ・ Complement of HMS Bounty ・ Complement receptor Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Complement component 4B ： ウィキペディア英語版 Complement component 4B Complement component 4B (Chido blood group) is a protein that in humans is encoded by the C4B gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=721 )〕 This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. (by RefSeq, Jul 2008 ).〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=retrieve&list_uids=721 )〕 ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Complement component 4B」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.